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Ambien Online

October 01 2024

Ambien is a fairly strong sleeping pill and sedative. The condition for dispensing from pharmacies is only with a prescription from the attending physician.

The drug Ambien is included in the pharmacotherapeutic group of hypnotics and sedatives. It is used in neurological practice to eliminate insomnia and problems falling asleep.


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Pharmacodynamics and pharmacokinetics


Zolpidem, the active ingredient in Ambien, is a hypnotic drug belonging to the cyclopyrrolones group. It has a number of therapeutic effects, including:

  • sleeping pills;
  • sedative;
  • tranquilizing;
  • anticonvulsant;
  • muscle relaxant.

These effects are closely related to the agonistic effect of zolpidem on the central nervous system. The main feature of the drug is that under its influence the period of falling asleep is significantly reduced. In parallel with this, the number of night and morning awakenings decreases.

Thus, in patients suffering from insomnia, the effect of zolpidem is expressed in a reduction in the duration of the 1st phase of sleep and an extension of the 2nd phase of sleep. In parallel with this, the preservation and prolongation of 3-4 deep stages of sleep occurs. Sleep occurs half an hour after taking the drug and lasts from 6 to 8 hours.

After taking the tablet, it is quickly and completely absorbed from the gastrointestinal tract. After 1.5-2 hours, its maximum concentrations in the blood plasma are reached. In this case, neither the timing of meals nor any other factors affect the absorption of the substance.


 
Indications and contraindications for use


Ambien is prescribed to patients suffering from sleep problems and difficulty falling asleep. The drug is effective for all types of insomnia:

  • transferable;
  • situational;
  • chronic.

It is strictly unacceptable to take the medicine:

  • if you are intolerant to any of the components of the drug;
  • patients with severe respiratory failure;
  • persons suffering from spontaneous sleep apnea;
  • patients with pseudoparalyticmyasthenia;
  • with severe renal and liver failure;

  • people with congenital galactose intolerance;
  • with Lapp-lactase deficiency;
  • with malabsorption of glucose-galactose;
  • during lactation;
  • throughout pregnancy.

The drug is intended for the treatment of sleep disorders in adult patients, so it is not prescribed to children under 18 years of age.


 
Detailed instructions for the use of the drug


The drug is intended for oral administration. You should take the tablet immediately before going to bed at night. The course of treatment should be as short as possible and not exceed 28 days. The dose of the medicine may be adjusted depending on its effectiveness.

Prolongation of therapy is possible, but only after a thorough assessment of the patient's condition. Treatment begins with the minimum effective dose, which is gradually increased to the desired values.


 
Duration of therapy


The length of time you take Ambien tablets depends on what type of insomnia they were prescribed for:

  1. For transient insomnia, the course of treatment lasts from 2 to 5 days.
  2. For the treatment of situational insomnia, the drug is prescribed in a course lasting from 2 to 3 weeks.
  3. For chronic insomnia, the duration of therapy is 4 weeks. But treatment can be prolonged after a re-examination by a neurologist and assessment of the patient’s condition.

Precautionary measures


When prescribing and taking tablets, special precautions should be taken in patients with:

  • alcohol or drug addiction;
  • arterial hypotension;
  • depression or other conditions accompanied by central nervous system depression;

  • mental disorders;
  • paradoxical reactions;
  • somnambulism;
  • sleepwalking.

Please note that the drug may be addictive. If it is abruptly discontinued, the so-called withdrawal syndrome may develop—some patients who stopped taking Ambien experienced rebound insomnia.

With such conditions, you should definitely contact a neurologist – you cannot try to fight them on your own, especially with the help of other medications, even if they are herbal.


 
Possible adverse reactions


The most common side effect of taking Ambien is a metallic or bitter taste in the mouth. Negative reactions can manifest themselves in the appearance of:

  • behavioral disorders;
  • speech disorders;
  • irritability;
  • aggressiveness;
  • delusional states;
  • disorders of consciousness;
  • causeless anxiety;
  • somnambulism;
  • feelings of euphoria;
  • headache;
  • ataxia;
  • confusion;
  • hallucinations;
  • decreased concentration;

  • drowsiness;
  • insomnia;
  • nightmares;
  • depression;
  • agitation;
  • voltage;
  • changes in sexual behavior.

Often, taking pills leads to weight loss, nausea, and stomach pain. In patients with respiratory failure, the drug may cause shortness of breath or dyspnea. If any ailments associated with treatment with Ambien occur, its use should be stopped immediately. Even a single case of side effects can cause harm to the patient’s health.

An overdose of Ambien is very dangerous, so you should not self-medicate if the drug is taken in an increased dose. The intensity of symptoms depends on the dose of medication taken. Thus, with a significant excess of the permissible volume of the drug, as well as with a systematic overdose, not only the intensity of clinical manifestations increases, but also the risk of developing a coma.

It is important to note that Ambien is not prescribed for use at home in patients with alcohol or drug addiction. Combining the medication with alcohol or drugs increases the risk of side effects and also makes an overdose potentially life-threatening.

 

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